Some of the most promising new therapies for warts (human papilloma virus-HPV) involves
using medications to prevent them from disabling the body's immune system
Now,it is thought that warts, may, similar to cancer , release substances known as immune
checkpoints which prevents the body's immune system from attacking and destroying them before
thjey are able to establish a foothold on or in the body.
Recent research indicates that recalcitrant warts in particular released an immune checkpoint
such as PD-L1(programmed cell death) which attacks the body's immune system and prevents the
body from killing the wart virus.
And, it is believed that drugs called immune checkpoint inhibitors can energize the immune
system to kill viral warts by blocking immune checkpoint proteins such as PDL-1 and PD1.
Therefore,it is hoped that we may be able to use these immune checkpoint inhibitors
to help the body's immune system to recognize the human papilloma virus. and destroiy it.
When these drugs are given internally to fight various types of cancer such as the merkel
cell carcinoma and malignant melanoma(see previous articles) ,they can be very effective but
can also have many potential side effects.
Hopefully, a topical(not internal) form will be developed and not lead to any untoiward
effects.
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