Posts for tag: acne

         The risk of antibiotic resistance in treating Acne and the "killing off"  of

the so-called  "good germs" in our body's gastrointestinal and respiratory

tracts-which in itself can lead to illness-has lead to the recommendation

that internal antibiotic use be limited to a few months.

          In fact, one of the main take aways from a 2015 study was that a

subantimicrobial release version of a popular acne drug called doxycycline 40 mgs

given once daily to patients 12 years of age or older with moderate to severe

inflammatory acne for 16 weeks had comparable efficacy to doxycycline 100mgs

daily for the same 16 week time period  with superior safety via markedly less

drug-related adverse events.

The following list of medications is certainly not all-inclusive since many different classes of

prescription and over-the-counter drugs can make the skin more sensitive to ultraviolet rays.

Some of the more popular photosensitizing medications include:

          Antibiotics: tetracycline,doxycycline hyclate(not the smaller-dose doxycycline found

in the brand name product "Oracea.") and sulfa-containing antibiotics such as trimethoprim/

sulfamethoxazole.

         Arthritis drugs: ibuprofen, naproxen

        Blood pressure/"water pill" drugs: hydrochlorthiazide(more a blood pressure drug than

a water pill) furosemide(more a water pill than a blood pressure drug).Both of these contain

sulfa,which is a photosensitizer.

       A recent study indicated that the calcium channel blocker nifedipine and the ACE

inhibitor lisinopril both increased sun-sensitivity and made users more likely to develop

lip cancer.

       Diabetes drugs: glipizide,glyburide, and chlorpropamide all contain sulfa and,therefore,

are more likely to be sun-sensitizers.

      Antihistamine:  the popular diphenhydramine

     Acne medications: include those related to Vitamin A such as  isotretinoin,tretinoin,and

acetretin.

    Anti-cancer(chemotherapy) drugs:  5-fluorouracil  and dacarbazine

    Psychiatric drugs such as the major tranquilizers chlorpromazine and the tricyclic 

antidepressants  desipramine and imipramine.

   External (topical) products such as scented or deordorant soaps, toiletries, cosmetics or fragrances

         In summary,  the benefit of these drugs probably outweighs the potential sun-senitivity side

effects (especially with the judicious use of sunscreens and sun exposure time). If not,they

should only be discontinued with the consent of the health care practitioner prescribing

them.

 

 

 



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