Posts for tag: cholesterol

By Robert J Weiss MD PC
February 20, 2016
Category: Uncategorized

             Rosacea (acne rosacea)  is a common skin disease characterized by redness and  often  in small  pus- filled bumps on the face mainly in adults who tend to flush and blush more often in response to triggers such as alcohol, hot or spicy foods, stress and heat including the sun. Therefore, at least # 30  sunscreens applied at least 30 minutes before sun exposure are a must.

                Rosacea  can also exist in an ocular form  resulting in red, watery, and itchy eyes

                 Recent studies indicate a link between many inflammatory conditions in the body  and on the skin including rosacea, psoriasis, and internal diseases with an increased cardiovascular disease risk such as hypertension, coronary artery disease and high cholesterol.

              In addition, this risk of cardiovascular disease in rosacea seems to be higher in male patients than female patients and is manifested by an increase risk of diabetes, stroke and narrowing of the arteries.

               One hypothesis for these findings is that chronic  inflammation may lead to changes in the lipo- proteins which transport cholesterol and other substances in the blood stream, thereby, decreasing their ability to remove cholesterol from the body.

                In my opinion, the main teaching point of all this is for patients with moderate to severe rosacea to get regular checkups with their healthcare practitioner.

A drug with the generic name tofacitnib citrate , which is in a class of drugs called

 Janus kinase inhibitors  which prevent the production of cytokines which mediate

 inflammation, is being used for a severe type of eczema called atopic dermatitis.

 Atopic dermatitis is a type of skin inflammation characterized by itching,red and

cracked skin with a preponderance for the back of the knees and front of the elbows.

 It has a definite genetic predisposition and many people with it are more prone to asthma

 and hayfever.

 Janus kinase inhibitors (JAK) are also being proposed for psoriasis, vitiligo (loss of skin

 pigment), and the type of hair loss called alopecia areata.

 In addition, Janus kinase  inhibitor drugs are used for rheumatoid arthritis.

 Although generally well tolerated, Janus kinase inhibitors can lead to opportunistic infections,

 malignancies, and elevated lipids (cholesterol, triglycerides). I

           Does chronic moderate to severe inflammation on the outside of the body (ie,the skin)

indicate significant inflammation on the inside of the body (ie,the internal organs ) ?

           Recent studies seem to be pointing in this direction (please see my  3 previous

posts on Psoriasis). In addition to these 3 articles another example of this skin-internal 

body correlation is that men with psoriasis seem to be more prone to the "wet" or more

serious (vs."dry" )  type of age-related macular degeneration of the eye.

          Another example involves  recent research indicating that moderate to severe

Acne Rosacea,the "adult" type of acne made worse by heat and sun-exposure vs. the

so-called teenage Acne Vulgarus-which,by the way,many  adults still have late in life,

is associated with coronary(heart) artery disease.

          And,the authors of the study  suggest that patients with Acne Rosacea be screened

for coronary vascular risk factors such as hypertension,diabetes,and  high cholesterol.

         In  fact,then, it is becoming more and more clear that any disorder with chronic

moderate to severe inflammation-whether external or internal- may be associated with

coronary artery disease risk and metabolic consequences.

         The bottom line again is  regular checkups with their healthcare provider and to report

any changes in body signs or symptoms at once.

Coming soon.

                  Most people know that shingles or herpes zoster occurs in people who had chicken pox (varicella) 

in the past and can occur years or decades later. And,shingles is more common in people over 65 years old 

and usually occurs only once .

                 Also,the rash,which usually follows a distribution of nerve endings,can be characterized by pain,

burning, numbness or tingling and is usually preceded by headache,fever,pain or malaise (a general

feeling of discomfort or uneasiness) . Herpes zoster (shingles) usually does not cross the midline of  the

body and presents as grouped vesicles (blisters).

                A recent study reports that patients who had shingles after age 40 had a 10 % higher risk for

myocardial infarction (heart attack) and a 15 % greater incidence of a TIA (mini-stroke or transient

ischemic attack).

              Those individuals who had shingles prior to age 40 were in much greater danger-a 50 %

higher chance of a heart attack and 2.4 times more prone to have a mini-stroke.

             The bottom line: if you have had shingles,get a cardiovascular checkup which should

include screening for risk factors including high blood pressure,cholesterol,diabetes, and

coronary artery disease.

 

                 

 

By Robert J Weiss MD PC
March 31, 2014
Category: Uncategorized

Welcome to the Blog of Robert J Weiss MD P.C

Whether you are an existing patient or searching for a dentist in the area, we’re excited you are here. With the dental industry advancing, we recognize the importance of keeping our patients and visitors up to date with all of the new and exciting things taking place in our practice.

As we move forward with our blog, we hope to promote dental awareness as a vital part of your healthy lifestyle. Here you will find a variety of articles and topics including dental news, advancements in dental technology and treatments, practical oral health advice and updates from our practice.

We hope you find our blog to be helpful, engaging and informational to ensure your best dental health. 

As always, feel free to contact our Robert J Weiss MD P.C office with any dental questions or concerns.



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