Posts for tag: skin biopsy

There are several methods of lightening dark skin spots. However, anyone with hyper pigmented spots on

 the skin should first have them checked by their dermatologist to rule out either precancer or skin cancer.

 This can sometimes be done by a simple visual examination. Or, it may require a skin biopsy. If  the 

 darkened skin areas are deemed to be benign, one or more of the following methods may be used

 to lighten them.

 A topical (i.e., applied from the outside to the skin) medication called hydroquinone, sometimes

 combined with a vitamin A derivative called tretinoin is one of the most effective, noninvasive

 methods of lightning dark skin spots.

  Other methods include the application of intense pulsed light and various types of lasers,

 chemical peels (especially those containing trichloroacetic acid   or glycolic acid). These

 peels can also help eliminate fine lines and wrinkling caused by sun exposure and/or aging of the skin.

 In addition, products containing azelaic acid, which is component of grains such as barley, rye

 and wheat, and vitamin C (ascorbic acid) can also have a skin lightening effect.

 One can also consider the use of an old remedy, lemon juice which contains citric acid and 

 has been used as a skin  lightener for a long time.

 However, one must be very careful with the application time when applying lemon juice

 to the skin  since it can dry out the skin and is a potent photosensitizer that can cause sunburn

 when exposed to the sun.






Mycoses  fungoides lymphoma is  a T cell (a type of white blood cell) lymphoma of the skin which often masquerades for many years as a  patchy or plaque like reddish and scaling rash – especially in the pelvic girdle area of the body before it metastasizes (spreads inward) to blood, lymph nodes, and visceral (internal body) sites. 

  Since it often appears like eczema or psoriasis and can have an itch component, the average time from onset to diagnosis  is 7 years.  And, it may be misdiagnosed as psoriasis, eczema, or even fungus.  A key to diagnosis is its unresponsiveness to conventional therapy of the aforementioned skin diseases . A skin biopsy is warranted in such instances and confirms the medical provider's clinical suspicions.

 Treatment options are varied depending on the stage of the disease and include ultraviolet  A light and a medicine  taken internally called psoralen (P –UVA), and topical nitrogen mustard   for early stages. 

More advanced  stages are treated with radiation therapy, chemotherapy, and even stem- cell – bone marrow transplantation.

 A procedure call extracorporeal photophoresis has even been utilized in which one's blood is treated with a photo- sensitizing agent  such as 8 – methoxy psoralen and then run through a machine where it is then irradiated with a specific wavelength of ultraviolet A light and then returned to the patient where  the irradiated T cells now have an antitumor action.